Outcomes of drug-induced acute pancreatitisa ten-year experience of an academic center

  1. Rubén Sánchez Aldehuelo 1
  2. Ana García García de Paredes 1
  3. Diego Rojo Lázaro 1
  4. Antonio Jesús Martínez Ortega 1
  5. Irene García de la Filia Molina 1
  6. Sergio López Durán 1
  7. Miguel Ángel Rodríguez Gandía 1
  8. Antonio López Sanromán 1
  9. Agustín Albillos Martínez 1
  1. 1 Hospital Universitario Ramón y Caja. Madrid, Spain
Revista:
Revista Española de Enfermedades Digestivas

ISSN: 2340-416,  1130-0108

Año de publicación: 2021

Volumen: 113

Número: 4

Páginas: 276-279

Tipo: Artículo

DOI: 10.17235/REED.2020.7443/2020 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Revista Española de Enfermedades Digestivas

Resumen

Background: drug-induced pancreatitis is an unexplored entity. Methods: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed. Results: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %. Conclusion: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.

Fuente de los datos: Dialnet