Social Cognition Mediates the Impact of Processing Speed and Sustained Attention on Global Functioning in Schizophrenia

  1. Alicia Ruiz-Toca
  2. Cristina Fernández-Aragón
  3. Ana Madriga
  4. Tate Halverson
  5. Roberto Rodríguez-Jiménez
  6. Guillermo Lahera
Revista:
Psicothema

ISSN: 0214-9915 1886-144X

Año de publicación: 2023

Volumen: 35

Número: 1

Páginas: 87-97

Tipo: Artículo

DOI: 10.7334/PSICOTHEMA2022.8 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Psicothema

Resumen

Los déficits en el procesamiento de la información, la atención sostenida y la cognición social tienen implicaciones importantes para el funcionamiento diario de las personas con esquizofrenia. El presente estudio analizó la relación entre velocidad de procesamiento, atención sostenida, cognición social y funcionamiento en personas clínicamente estables con esquizofrenia. Método: Noventa personas con esquizofrenia y 100 controles sanos completaron una batería de pruebas para evaluar síntomas clínicos, velocidad de procesamiento, atención sostenida, cognición social y funcionamiento. Se utilizaron GLMM y SEM para evaluar las relaciones entre variables. Resultados: Las personas con esquizofrenia tuvieron un peor rendimiento en todos los resultados cognitivos. La velocidad de procesamiento y la atención sostenida, juntas en una variable latente, tuvieron un fuerte efecto sobre el funcionamiento (Beta = 0,32; p < 0,05). La cognición social también tuvo un fuerte efecto sobre el funcionamiento (Beta = 0,29; p < 0,001) en el modelo de mediación, que mostró mejores índices de ajuste que el modelo que incluía solo neurocognición (e.g. RMSEAbasic = 0.131 y RMSEAmediator = 0.054). Conclusiones: El efecto mediador de la cognición social sobre la relación entre la velocidad de procesamiento, la atención sostenida y el funcionamiento sugiere la importancia de incluir ambos dominios junto con la cognición social como objetivos de tratamiento en las intervenciones de rehabilitación.

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