Publications in collaboration with researchers from Hospital Universitario de la Princesa (13)

2022

  1. Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment

    Antioxidants, Vol. 11, Núm. 9

2020

  1. In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases

    ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801

2019

  1. Molecular Scaffolds as Double-Targeting Agents For the Diagnosis and Treatment of Neuroblastoma

    Angewandte Chemie - International Edition, Vol. 58, Núm. 10, pp. 3067-3072

  2. New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

    Journal of Medicinal Chemistry, Vol. 62, Núm. 24, pp. 11416-11422

  3. Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy

    Molecules, Vol. 24, Núm. 8

2017

  1. Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

    Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12765-12769

2016

  1. The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

    Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9967-9973

2013

  1. Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: Effect against amyloid-β-induced neurotoxicity

    ACS Chemical Neuroscience, Vol. 4, Núm. 4, pp. 547-565

2012

  1. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

    European Journal of Medicinal Chemistry, Vol. 52, pp. 251-262

  2. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763

2011

  1. Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 12, pp. 6119-6130

  2. Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 4665-4668

2010

  1. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives

    Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143