Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
DISCOBAC


Universitat Autònoma de Barcelona
Barcelona, EspañaPublications in collaboration with researchers from Universitat Autònoma de Barcelona (6)
2024
-
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555
2014
-
Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 75, pp. 82-95
-
Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561
2012
-
Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine
European Journal of Medicinal Chemistry, Vol. 52, pp. 251-262
2011
-
Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 4665-4668
2002
-
Ligand-receptor interaction at the neural nicotinic acetylcholine binding site: A theoretical model
Journal of Molecular Graphics and Modelling, Vol. 21, Núm. 2, pp. 111-118