Cáncer colorrectal

  1. Molina Villaverde, R.
  2. Jiménez Gordo, A.M.
  3. López Gómez, M.
  4. Álvarez-Mon Soto, M.
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2017

Título del ejemplar: Enfermedades oncológicas (II) Tumores digestivos

Serie: 12

Número: 32

Páginas: 1911-1918

Tipo: Artículo

DOI: 10.1016/J.MED.2017.04.012 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

Resumen Introducción El cáncer colorrectal (CCR) es la segunda causa de muerte en el mundo por un tumor maligno. Hay casos tanto esporádicos como hereditarios. Se ha asociado a distintos factores ambientales, entre los que destaca una baja ingesta de fibra. Diagnóstico Los estudios de cribado con colonoscopia han de hacerse con regularidad, especialmente en los pacientes de alto riesgo. Tratamiento En la enfermedad localizada, la cirugía es el tratamiento de elección. En los estadios III, el tratamiento adyuvante con quimioterapia ha demostrado beneficio en la supervivencia. Los pacientes con estadio IV tienen opciones de curación si las metástasis pueden ser resecadas, con una supervivencia a 5 años cercana al 50%. Para el manejo de la enfermedad metastásica (estadio IV) se utilizan combinaciones de quimioterapia y fármacos biológicos.

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