Sarcoidosis

  1. Albarrán, F. 1
  2. Abassi Pérez, A. 1
  3. Pérez Gómez, A. 1
  4. Álvarez-Mon Soto, M. 1
  1. 1 Servicio de Reumatología y Autoinmunidad, Hospital Universitario Príncipe de Asturias, Universidad de Alcalá, Alcalá de Henares, Madrid, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2021

Título del ejemplar: Enfermedades del sistema inmune (V)

Serie: 13

Número: 32

Páginas: 1824-1836

Tipo: Artículo

DOI: 10.1016/J.MED.2021.04.012 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

La sarcoidosis es una enfermedad sistémica de etiología desconocida, con una patogenia mediada por el sistema inmunitario y con desarrollo de lesiones tisulares con granulomas epitelioides no caseificantes. La patocronia y la expresión clínica de la enfermedad son variables. La afectación más frecuente es la pulmonar, que puede coexistir con manifestaciones extratorácicas como las cutáneas, oculares, hepáticas, cardíacas y/o del sistema nervioso central. El diagnóstico se fundamenta en la clínica del enfermo y en la evidencia del daño tisular y del patrón histológico granulomatoso, con exclusión de otras posibles etiologías. El tratamiento de la enfermedad se establece por la gravedad, la evolución y la localización de los órganos afectados y se fundamenta en el empleo de corticoides e inmunosupresores.

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Fuente de los datos: Dialnet