La historia del linfocito en el siglo XX

Abstract

Introduction. The lymphocyte as such emerged in the early twentieth century, thanks to authors like Pappenheimer. Jobs that marked its history and its implications to physiological and clinical level, are studied. Objectives. Study the events surrounding the discovery of lymphocyte, investigate the phases of knowledge on lymphocyte cell and show the (current) clinical assessment of the level, are studied. Objectives. Study the events surrounding the discovery of lymphocyte, investigate the phases of knowledge on lymphocyte cell and show the (current) clinical assessment of the lymphocyte. Material and methods. After verifying the feasibility of the project, the initial search was done with the word lymphocyt * in PubMed and Scopus, the book was made in Google Books, complete with specific themes or authors in Pubmed, Scopus or Dialnet when the subject requires development. Results. Studies in relation to lymphocyte have gone parallel to technical advance. Initially interested lyphoid morphology, their response to various stimuli and their role in immunity taking as model tuberculosis and cancer. The electron microscope reveal its ultrastructure , and techniques such as electrophoresis and autoradiography, numerous investigations that help model tuberculosis and cancer. The electron microscope reveal its ultrastructure , and techniques such as electrophoresis and autoradiography, numerous investigations that help facilitate a better understanding of the disease. Lymphoid cell cultures or monoclonal antibodies are some of the achievements. Conclusions. Works about the lymphocyte have helped to understand physiological and pathological mechanisms, to advance research and a ddressing diseases Lymphocytes are still the subject of research.