Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study
- Julia Serrano 1
- Rosa Mª López-Pintor Muñoz 2
- Mónica Fernández Castro 3
- Lucía Ramírez Martínez Acitores 2
- Mariano Sanz Alonso 2
- Elisabeth Casañas Gil 2
- Jesús Alberto García 4
- Sheila Recuero 5
- Cristina Bohórquez Heras 6
- Gonzalo Hernández Vallejo 2
- 1 pHD student. Department of Dental Clinical Specialties, School of Dentistry, Complutense University, Madrid, Spain
- 2 Department of Dental Clinical Specialties, School of Dentistry, Complutense University, Madrid, Spain
- 3 Rheumatology Service, Hospital Puerta de Hierro, Madrid, Spain
- 4 Rheumatology Service, Hospital de la Princesa, Madrid, Spain
- 5 Rheumatology Service, Fundación Jiménez Díaz, Madrid, Spain
- 6 Rheumatology Service, Hospital Principie de Asturias, Alcalá de Henares, Madrid
ISSN: 1698-6946
Datum der Publikation: 2020
Ausgabe: 25
Nummer: 1
Seiten: 17
Art: Artikel
Andere Publikationen in: Medicina oral, patología oral y cirugía bucal. Ed. inglesa
Zusammenfassung
To evaluate the presence of oral lesions in a group of patients with primary Sjögren’s syndrome (pSS) and compare these results with a matched control group (CG). An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) diagnosed according to the American European Criteria (2002), and 122 matched control patients (120 women, 2 men, mean age 60.02±13.13) were included. Demographic and medical data, oral lesions and salivary flow rate were collected. Compared with the controls, pSS patients were 3.95 more likely to have oral lesions (OR 3.95; 95% CI 2.06-7.58; p=0.0001). 57.4% pSS patients presented oral lesions compared to 25.4% in CG. The most common were candidiasis (13.1% vs 2.5%), traumatic lesions (13.1% vs 4.1%), apthae (8.2% vs 0), and fissuration of the tongue (8.2% vs 0.8%). pSS patients with oral lesions had lower salivary flow levels (stimulated and unstimulated), although these differences were not significant. Significant associations were found between the presence of oral lesions and systemic manifestations and history of parotid gland enlargement in pSS patients. pSS patients suffer more oral lesions than general population and these lesions may aggravate the pSS disease.
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