Actualización en cáncer de próstata
- Martínez Amores Martínez, Brezo
- Durán Poveda, Manuel
- Sánchez Encinas, Miguel
- Molina Villaverde, Raquel
ISSN: 0304-5412
Year of publication: 2013
Issue Title: Enfermedades oncológicas (III): tumores genitourinarios, melanoma
Series: 11
Issue: 26
Pages: 1578-1587
Type: Article
More publications in: Medicine: Programa de Formación Médica Continuada Acreditado
Abstract
Prostate cancer is considered to be one of the most important medical problems of the male population with very high incidence after 65 years of age. Most of the cases correspond to adenocarcinomas. They gene rally begin in the peripheral area of the prostate gland. From the histological point of view, the Gleason grading system makes it possible to numerically classify the tumor aggressivity. The tumors are generally asymptomatic until advanced stages of treatment. They are usually detected by endorectal ultrasound-guided prostate biopsy performed due to elevated PSA value in blood tests. Bone metastases are the most frequently found form of metastatic involvement. Localized tumors may be treated by prostatectomy and/or radiotherapy. Prostate cancer is a hormone-dependent tumor so that disseminated tumors respond to hormonal manipulations over long periods. Chemotherapy has been demonstrated to increase survival in these patients after hormone failure.