Funciones de los linfocitos B
- Prieto Martín, Alfredo
- Barbarroja Escudero, José
- Barcenilla Rodríguez, Hugo
- Díaz Martín, David
ISSN: 0304-5412
Année de publication: 2013
Titre de la publication: Enfermedades del sistema inmune (I): fundamentos fisiológicos
Serie: 11
Número: 28
Pages: 1752-1759
Type: Article
D'autres publications dans: Medicine: Programa de Formación Médica Continuada Acreditado
Résumé
B Iymphocytes are responsible for humoral immunity. Their primary function is the defence of the host against germs by means of the secretion of antibodies that recognise the antigenic molecules of the pathogens. B Iymphocytes have additional functions such as the presentation of antigens to T Iymphocytes, the negative regulation of inflammatory responses and the regulation of responses to autoantigens. B cells produce antibodies to various isotypes that are distributed and located in various parts of our body and trigger various effector functions, such as the activation of the complement, and various cell responses mediated by antibody receptors, such as the phagocytosis of microorganisms and immune complexes and the exocytosis of mediators and cytotoxins.