Funciones efectoras de los linfocitos T
- Díaz Martín, David
- Barcenilla Rodríguez, Hugo
- Borrero Corte, M. José
- Álvarez de Mon Soto, Melchor
ISSN: 0304-5412
Year of publication: 2013
Issue Title: Enfermedades del sistema inmune (I): fundamentos fisiológicos
Series: 11
Issue: 28
Pages: 1742-1751
Type: Article
More publications in: Medicine: Programa de Formación Médica Continuada Acreditado
Abstract
We begin this chapter by describing the recirculation of T Iymphocytes and explaining how particular populations of T Iymphocytes selectively enter Iymph nodes and specific tissues, a phenomenon known as Iymphocytic accommodation or addressing. We examine in detail differentiation following an antigen encounter, specifically the three functional states of T Iymphocytes: virgin, memory and effector. We pay special attention to the effector functions of the helper and cytotoxic T Iymphocytes, as well as their differentiation into Th1, Th2 and Th17 Iymphocytes. Finally, we briefly examine the T gamma delta and NKT Iymphocytes as well as immunological memory and the shutdown of immune responses.