Evaluación mediante electrorretinografía de la toxicidad del azul tripán en la cirugía del agujero macular

  1. M.S. Figueroa
  2. G. Rebolleda
  3. S. Noval
  4. I. Contreras
Aldizkaria:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Argitalpen urtea: 2008

Alea: 83

Zenbakia: 11

Orrialdeak: 659-664

Mota: Artikulua

DOI: 10.4321/S0365-66912008001100006 DIALNET GOOGLE SCHOLAR lock_openSarbide irekia editor

Beste argitalpen batzuk: Archivos de la Sociedad Española de Oftalmologia

Laburpena

Purpose: Concern has been raised about the retinal toxicity of vital dyes. We designed a prospective study to determine the possible toxicity of trypan-blue (TB) in macular hole surgery with TB-assisted internal limiting membrane (ILM) peeling through the performance of electroretinograms (ERGs). Methods: Patients diagnosed with a macular hole underwent ophthalmological evaluation prior to surgery and at 6 months follow-up. All patients underwent vitrectomy and ILM-staining under air. All phakic patients underwent phacoemulsification and IOL implantation simultaneously. There were two study groups: In group 1, ILM-staining was performed with 0.06% TB, while in group 2 the procedure was performed with 0.15% TB. Preoperative ERG recordings were measured in the week prior to surgery. Postoperative ERGs were measured 3 to 6 months after surgery. The ERG data between eyes with macular hole and fellow eyes were compared in the pre- and post-operative stages. Visual acuity (VA) changes in both groups were evaluated. Results: Nine patients were recruited in each group. VA improved significantly in both groups, with more than 65% of patients improving more than 2 lines. There were no statistical differences in VA gain between groups or in ERG values between affected and fellow eyes. Conclusion: No significant retinal toxicity of TB staining could be clinically detected

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