Cáncer de pulmón no microcítico
- Expósito, F. Navarro
- González, J.L. López
- Castillo, C.
- Losada, C.
- Soto, M. Álvarez-Mon
ISSN: 0304-5412
Año de publicación: 2017
Título del ejemplar: Enfermedades oncológicas (I) Cáncer de pulmón. Cáncer de cabeza y cuello
Serie: 12
Número: 31
Páginas: 1811-1824
Tipo: Artículo
Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado
Resumen
Abstract Introduction Lung cancer has become a major public health problem due to its high incidence and mortality rate. This is the leading cause of cancer-related mortality, in general, worldwide. Etiopathogeny There are a large number of environmental factors associated with the development of lung cancer, of which smoking is the most important. Histology A total of 85% of the lung cancers diagnosed correspond to non-small cell carcinomas and, within these, the most frequent histological type is adenocarcinoma, with an increase in its incidence in recent years. Treatment At diagnosis, more than 50% present with locally advanced or metastatic disease, with a survival rate of 15% at 5 years. Non-small cell lung cancer (NSCLC) is a category that differs in terms of clinical course and prognosis and, therefore, offers different possible treatment options, based on a combination of surgery, chemotherapy and radiotherapy. In recent years, the identification of oncogenic molecular targets has made it possible to develop personalised treatments.
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