Cáncer de pulmón no microcítico

  1. Expósito, F. Navarro
  2. González, J.L. López
  3. Castillo, C.
  4. Losada, C.
  5. Soto, M. Álvarez-Mon
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2017

Título del ejemplar: Enfermedades oncológicas (I) Cáncer de pulmón. Cáncer de cabeza y cuello

Serie: 12

Número: 31

Páginas: 1811-1824

Tipo: Artículo

DOI: 10.1016/J.MED.2017.04.001 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

Resumen Introducción El cáncer de pulmón se ha convertido en un importante problema de salud pública debido a su elevada incidencia y mortalidad. Es la principal causa de mortalidad relacionada con el cáncer en todo el mundo. Etiopatogenia Existe un amplio número de factores ambientales asociados al desarrollo de cáncer de pulmón, de todos ellos el hábito tabáquico es el más importante. Histología El 85% de los cánceres de pulmón diagnosticados corresponden a carcinomas de células no pequeñas y, dentro de estos, el tipo histológico más frecuente es el adenocarcinoma, con un aumento de su incidencia en los últimos años. Tratamiento En el momento del diagnóstico, más del 50% se presentan con enfermedad localmente avanzada o metastásica, con una supervivencia del 15% a 5 años. El cáncer de pulmón no microcítico (CPNM) constituye un grupo de entidades que difieren en cuanto al curso clínico y pronóstico y, por tanto, con diferentes posibilidades terapéuticas, basadas en la combinación de la cirugía, quimioterapia y radioterapia. En los últimos años, la identificación de dianas moleculares oncogénicas ha permitido el desarrollo de tratamientos personalizados.

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