Protocolo diagnóstico y despistaje de las acidosis tubulares
- Gili, B. Quiroga
- Sevillano, B. Hernández
- del Valle, K.M. Pérez
- de la Fuente, G. de Arriba
ISSN: 0304-5412
Year of publication: 2019
Issue Title: Enfermedades nefrourinarias (V)Enfermedades renales tubulointersticiales.Nefropatías hereditarias y congénitas
Series: 12
Issue: 83
Pages: 4899-4901
Type: Article
More publications in: Medicine: Programa de Formación Médica Continuada Acreditado
Abstract
Renal tubular acidosis is a group of tubular disorders causing acid-base balance and electrolyte disturbances varying according with tubular segment involved. Etiology can be primary (genetic origin) or secondary to diseases or toxic substances. Overall, they present with hyper-chloremia and a normal plasma anion gap, meanwhile in chronic forms hypercalciuria and nephrolithiasis are detected. They are classified in: type I (characterized by the inability to lower urinary pH), type II (characterized by a decreased renal HCO3− threshold), and type IV (pseudohypoaldosteronism). Bicarbonate replacement and management of ionic disorders are required for their treatment.
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