Enfermedades renales tubulointersticiales. Formas crónicas

  1. de la Fuente, G. de Arriba
  2. Sevillano, B. Hernández
  3. del Valle, K.M. Pérez
  4. Gili, B. Quiroga
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2019

Título del ejemplar: Enfermedades nefrourinarias (V)Enfermedades renales tubulointersticiales.Nefropatías hereditarias y congénitas

Serie: 12

Número: 83

Páginas: 4872-4877

Tipo: Artículo

DOI: 10.1016/J.MED.2019.06.021 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

In chronic tubulointerstitial kidney diseases (CTKD), primary damage is on, commonly, tubules and interstitium causing a range of clinical features. However, several conditions causing glomerular and vascular damage can provoke secondary chronic tubulointerstitial kidney, often associated with poor long-term prognosis. The etiology of CTKDs is very diverse and includes urological, metabolic, pharmacologic causes, systemic diseases and physicochemical factors, among others. Since kidney biopsy is unspecific, clinical suspicion and imaging tests are basis of its diagnosis. Since there are hardly any treatments that can inhibit the mechanisms of interstitial fibrosis, therapeutic options are damage prophylaxis, treatment of underlying disease, and control of the damage risk factors.

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