Lipoatrofia semicircular: una revisión sistemática de la literatura

  1. Rafael Díaz Sarmiento 1
  2. Rafael Peña Rodríguez 1
  3. Ángel Asúnsolo del Barco 1
  1. 1 Escuela Nacional de Medicina del Trabajo. Madrid. España
Journal:
Medicina y seguridad del trabajo

ISSN: 0465-546X,  1989-7790

Year of publication: 2011

Volume: 57

Issue: 222

Pages: 77-94

Type: Article

DOI: 10.4321/S0465-546X2011000100008 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Medicina y seguridad del trabajo

Abstract

Introduction: The semicircular lipoatrophy (LS) is a benign disorder of the subcutaneous tissue with unkvown cause. It is characterized by unilateral o bilateral semicircular depressions in the anterolateral side of the thighs. It is related to environmental labor conditions, repeated microtraumas and personal factors. We conducted this systematic review of the scientific literature to characterize the existing knowledge. Methods: Systematic Review. Databases: IBECS, IBSST, LILACS, IME, OSH-UPDATE, ISI-WOK, PubMed, CIS-DOC and Cochrane. We included articles about semicircular lipoatrophy related to working and environmental conditions. We used the levels of scientific evidence of the Scottish Intercollegiate Guidelines Network. Results: 66 articles were recovered. Only 22 fulfilled the inclusion criteria: Fifteen with evidence level 3 and 7 with evidence level 4. Seven studies were series of cases and 8 were unique case reports. All of them added 838 cases, informed between 1982-2010. The principal risk factors for LS are repetitive microtrauma, low relative humidity and electricity in modern office buildings. The semicircular depressions occur in the anterolateral side of thighs, without alteration of the skin and muscles, mostly in women (85%), without inflammatory signs and with unspecific histopathology. The magnetic resonance, x rays and the antinuclear antibodies are negative. The diagnosis is clinical, supported by ultrasonography. Psychological treatment and physical therapy can be useful. The preventive measures of greater impact are controlling risk factors. Conclusions: Insufficient scientific evidence exists about the causes of LS. It is a prevalent disorder that generates alarm, related to workplace conditions. It is necessary to continue investigating about causative agents.

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