Validación clínica del test Endofaster® como método diagnóstico rápido de la infección por Helicobacter pylori
- Eugenia Sánchez Rodríguez 1
- Rubén Sánchez Aldehuelo 1
- Raquel Ríos León 1
- Rosa María Martín Mateos 1
- Ana García García de Paredes 1
- Carlos Martín de Argila 1
- A. Caminoa-Lizarralde 1
- Agustín Albillos Martínez 1
- Enrique Vázquez Sequeiros 1
- 1 Hospital Universitario Ramón y Cajal. Madrid
ISSN: 2340-416, 1130-0108
Any de publicació: 2020
Volum: 112
Número: 1
Pàgines: 23-26
Tipus: Article
Altres publicacions en: Revista Española de Enfermedades Digestivas
Resum
Background: this study aimed to evaluate the diagnostic accuracy of the Endofaster® for the detection of Helicobacter pylori. Methods: during upper gastrointestinal endoscopy, gastric juice was aspirated to perform an analysis using the Endofaster®. This test was considered as positive when the ammonium concentration was > 67 ppm, negative when < 57 ppm and weakly positive between 57 and 67. Biopsy specimens were also taken as the gold standard. Results: among the 86 patients enrolled in the study, the Endofaster® result was positive in 23.7%, negative in 54.7% and weakly positive in 11.6%, whereas infection was detected via histology in 38.4% of patients. The accuracy was 81.4%, with a Kappa value of 0.57. Conclusions: the Endofaster® could be useful to perform a rapid diagnosis of Helicobacter pylori infection (area under the curve = 0.81).