Hipotiroidismo

  1. Trifu, D.S. 1
  2. Gil-Fournier Esquerra, N. 2
  3. Peláez Torres, N. 2
  4. Álvarez Hernández, J. 2
  1. 1 Sección de Endocrinología y Nutrición, Hospital Comarcal de Melilla, Melilla, España
  2. 2 Sección de Endocrinología y Nutrición, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2020

Issue Title: Enfermedades endocrinológicas y metabólicas (I)Patología tiroidea

Series: 13

Issue: 13

Pages: 727-734

Type: Article

DOI: 10.1016/J.MED.2020.07.003 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Abstract

Hypothyroidism is the most common endocrine disorder both in primary and specialized care. A suitable knowledge of their pathophysiology and natural history allows us to distinguish between diseases with a self-limited or indolent presentation from those requiring closer attention and management, (especially multi-pathological patient, elderly or pregnant woman). We need to learn to decide with ease when to perform serum TSH determinations as screening or as follow-up in already diagnosed patients, to make appropriate treatment modifications and to consult or refer to the specialist in case of doubts. In most cases, diagnosis and treatment are easy, however differential diagnosis have to be taken in to account. To treat or not to treat, is a medical decision. Fluent patient-physician communication is crucial, since treatment is often chronic.

Bibliographic References

  • Brent GA, Reed Larsen P, Davis TF. Hypothyroidism and thyroiditis. En: Kronenberg HM, editor. Williams Textbook of endocrinology. 11th ed. Philadelphia: Saunders Elsevier; 2008. p. 377-405.
  • Ross DS. Diagnosis of and screening for hypothyroidism in non-pregnant adults. En: Cooper DS, Mulder JE, editors. UpToDate [Internet] 2020 [citado 19 de febrero de 2020]. Disponible en: https://www.uptodate.com/contents/diagnosis-of-and-screening-for-hypothyroidism-in-nonpregnant-adults
  • Garber JR, Cobin RH, Gharib H, Hennessey JV, Klein I, Me-chanick JI, et al; American Association Of Clinical Endocrinologists And American Thyroid Association Taskforce On Hypothyroidism In Adults. Clinical practice guideliness for hypothyroidism in adults: cosponsored by the american association of clinical endocrinologist and the american thyroid associatio. Thyroid. 2012;22(12):1200-35.
  • Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, et al. Serum TSH, T(4), and thyroid antibodies in the Uni-ted States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab. 2002; 87(2):489-99.
  • Jonklass J, Bianco AC, Bauer AJ, Burman KD, Cappola AR, Celi FS, et al; American Thyroid Association Task Force on Thyroid Hor-mone Replacement. Guideliness for the treatment of hypothyroi-dism: prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. Thyroid. 2014;24(12):1670-751.
  • Bekkering GE, Agoritsas T, Lytvyn L, Heen AF, Feller M, Moutzouri E, et al. Thyroid hormones treatment for subclinical hypothyroidism: a cli-nical practice guideline. BMJ. 2019;365: I2006.
  • Elviro Peña MR, Guijarro de Armas mg. Hipotiroidismo. En: Cano Rodríguez I, coordinador. Manual de endocrinología y nutri-ción de la SEEN. 2018.