Protocolo diagnóstico y terapéutico del síndrome seco

  1. Pijoan Moratalla, C.M. 1
  2. Blanco Cáceres, B.A. 1
  3. Revenga Martínez, M. 2
  4. Vázquez Díaz, M. 1
  5. Bachiller Corral, F.J. 2
  1. 1 Servicio de Reumatología. Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS). Hospital Universitario Ramón y Cajal, Madrid, España
  2. 2 Servicio de Reumatología. Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS). Hospital Universitario Ramón y Cajal, Madrid, España Departamento de Medicina y Especialidades Médicas. Universidad de Alcalá. Alcalá de Henares, Madrid, España
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2021

Series: 13

Issue: 30

Pages: 1730-1734

Type: Article

DOI: 10.1016/J.MED.2021.03.034 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Abstract

Sicca syndrome is defined as the presence of objective symptoms of dryness at different levels, most commonly in the ocular region and oral cavity. Xerophthalmia and xerostomia are defined as the subjective sensation of oral or ocular dryness, respectively. Dryness can be idiopathic, have a pharmacological origin or be secondary to an autoimmune disease such as Sjögren's Syndrome. Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic infiltration and progressive destruction of the salivary and lacrimal glands. Sicca syndrome requires a multidisciplinary cross-sectional approach since the treatment is symptomatic and depending on the involvement that the patient presents, it can be managed by different specialists.

Funding information

Bibliographic References

  • Afonso AA, Monroy D, Stern ME, Feuer WJ, Tseng SC, Pflugfelder SC. Correlation of tear fluorescein clearance and Schirmer test scores with ocular irritation symptoms. Ophthalmol. 1999;106(4):803-810.
  • Feenstra RP, Tseng SC. Comparison of fluorescein and rose bengal staining. Ophthalmology. 1992;99(4):605-617.
  • Kim J, Foulks GN. Evaluation of the effect of lissamine green and rose bengal on human corneal epithelial cells. Cornea. 1999;18(3):328-832.
  • Goren MB, Goren SB. Diagnostic tests in patients with symptoms of keratoconjunctivitis sicca. Am J Ophthalmol. 1988;106(5): 570-574.
  • Aung W, Yamada I, Umehara I, Ohbayashi N, Yoshino N, Shibuya H. Sjögren’s syndrome: comparison of assessments with quantitative salivary gland scintigraphy and contrast sialography. J Nucl Med. 2000;41(2):257-262.
  • Amigo MC, Vidal M, Martinez Lavin M. Minimally invasive salivary gland biopsy technique. J Clin Rheumatol. 2002;8(4):236.
  • Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, 2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren’s Syndrome: a consensus and datandriven methodology involving three international patient cohorts. Arthritis Rheumatol. 2017;69(1):35-45.
  • Hong S, Kim T, Chung SH, Kim EK, Seo KY. Recurrence after topical nonpreserved methylprednisolone therapy for keratoconjunctivitis Sicca in Sjögren’s syndrome. J Ocul Pharmacol Ther. 2007;23(1):78-82.
  • Kim EC, Choi JS, Joo CK. A comparison of vitamin A and cyclosporine a 0.05% eye drops for treatment of dry eye syndrome. Am J Ophthalmol. 2009;147(2):206-213.e3.
  • Cho YK, Huang W, Kim GY, Lim BS. Comparison of autologous serum eye drops with different diluents. Curr Eye Res. 2013;38(1):9-17.