Coagulación intravascular diseminada como forma de presentación de leucemia aguda promielocíticaevaluación y tratamiento
- Celia Martínez Vázquez 1
- Marta Calleja Charavia 1
- Patricia García Ramírez 1
- Julio García Suarez 1
- 1 Facultad de Medicina y Ciencias de la Salud, Universidad de Alcalá
ISSN: 2530-2787
Ano de publicación: 2021
Volume: 6
Número: 1
Páxinas: 156-161
Tipo: Artigo
Outras publicacións en: RIECS: Revista de Investigación y Educación en Ciencias de la Salud
Resumo
We present the case of a 29-year-old man admitted to our center for hematuria with coagulopathy, mild leukopenia and moderate thrombopenia. A diagnosis of disseminated intravascular coagulation (DIC) secondary to Acute Promyelocytic Leukemia (APL) was made. Bleeding episodes due to DIC are one of the main causes of mortality at diagnosis in patients with APL. Currently there are lines of treatment with Arsenic Trioxide (ATO) and trans-retinoic acid (ATRA) that have replaced conventional chemotherapy regimens, with a decrease in bleeding rates. Therefore, an early diagnosis and treatment of DIC entails an increase in survival in these patients.