Afectación renal en la diabetes mellitus

  1. Barrio, F. Moreno
  2. Torres, C. Castillo
  3. Esparragoza, J.K. Peña
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2019

Serie: 12

Número: 80

Páginas: 4735-4744

Tipo: Artículo

DOI: 10.1016/J.MED.2019.05.031 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

Resumen La diabetes mellitus se ha convertido en un importante problema de salud pública con más de 140 millones de personas afectas en la actualidad. Esta cifra puede llegar al 4% de la población mundial en 2030. La nefropatía diabética (ND) es la primera causa de enfermedad renal crónica terminal y de inicio de terapia sustitutiva renal. La ND puede aparecer tanto en la DM tipo 1 como en la DM tipo 2. El seguimiento precoz de los pacientes, a través de la determinación periódica de microalbuminuria y estimación del filtrado glomerular, ayudará a la detección precoz de la ND en la fase clínica inicial en la que aún es potencialmente reversible la proteinuria, impidiendo la progresión a la insuficiencia renal. En este sentido, es muy importante llevar a cabo un enfoque terapéutico multifactorial en el paciente diabético, con un control estricto de la glucemia, de las cifras de presión arterial y de los factores de riesgo vascular. Los fármacos bloqueantes del eje renina-angiotensina-aldosterona siguen teniendo un papel fundamental en el tratamiento de la diabetes, siendo los antihipertensivos de primera elección en estos pacientes.

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