Protocolo de manejo clínico del síndrome confusional en el lupus eritematoso sistémico

  1. Movast Hajkhan, A. 1
  2. Bohórquez Heras, C. 1
  3. García Castañeda, N. 1
  4. Pérez Gómez, A. 1
  1. 1 Servicio de Enfermedades del Sistema Inmune-Reumatología, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Any de publicació: 2021

Títol de l'exemplar: Enfermeades del sistema inmune (IV)

Sèrie: 13

Número: 31

Pàgines: 1789-1792

Tipus: Article

DOI: 10.1016/J.MED.2021.04.007 DIALNET GOOGLE SCHOLAR

Altres publicacions en: Medicine: Programa de Formación Médica Continuada Acreditado

Resum

Acute confusional syndrome (ACS) is one of the 19 neuropsychiatric syndromes associated with systemic lupus erythematosus (SLE). It consists of impaired level of consciousness and attention, ranging from mild disturbance to coma. The prevalence of this manifestation in patients with SLE is 1.8% to 4.7%. When a case of ACS in a patient with SLE presents, it is often difficult to differentiate whether the aetiology is CNS involvement secondary to lupus activity or other causes. The differential diagnosis is very broad and includes infections, metabolic disorders, disorders secondary to drugs (especially glucocorticoids) and vascular disorders. The treatment of choice is a combination of glucocorticoids and an immunosuppressant, with cyclophosphamide being the most used drug.

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Fuente de los datos: Dialnet