Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
- Ma, Y.
- Josa-Prado, F.
- Essif, J.N.
- Liu, S.
- Li, S.
- Lucena-Agell, D.
- Chan, P.Y.
- Goossens, K.
- Hortigüela, R.
- Matesanz, R.
- Wang, Y.
- Gago, F.
- Wang, H.
- Risinger, A.
- Diaz, J.F.
- Fang, W.-S.
Journal:
European Journal of Medicinal Chemistry
ISSN: 1768-3254, 0223-5234
Year of publication: 2023
Volume: 259
Type: Article