Cáncer renal

  1. Peñas Pita da Veiga, M. 1
  2. Nalda Arija, I. 1
  3. Bernier García, L. 1
  4. Chara Velarde, L. 1
  5. Cassinello Espinosa, J. 1
  1. 1 Unidad de Oncología Médica, Hospital Universitario de Guadalajara, Guadalajara, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2021

Título del ejemplar: Enfermedades oncológicas (III) Tumores genitourinarios

Serie: 13

Número: 26

Páginas: 1431-1440

Tipo: Artículo

DOI: 10.1016/J.MED.2021.02.011 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumen

El cáncer de riñón es la séptima neoplasia en frecuencia y es más frecuente en varones. Se desconoce la etiología exacta de esta enfermedad, aunque se ha podido establecer su relación con el tabaco o la obesidad. Un 2% son hereditarios, asociados a síndromes genéticos, como la enfermedad de von Hippel-Lindau. En el 50% de los casos se diagnostican como incidentalomas al realizar pruebas de imagen por otros motivos. El cáncer renal de células claras es la histología más frecuente. Se estadifica según el sistema TNM de la AJCC y en base a la evaluación del riesgo (bajo, intermedio o alto según la escala del MSKCC). El tratamiento del carcinoma renal localizado es eminentemente quirúrgico y, en base a los estudios actuales, no hay evidencia para la adyuvancia. El tratamiento de la enfermedad avanzada se basa en el empleo de la inmunoterapia y los inhibidores de la tirosinquinasa (TKI) según el grupo de riesgo de cada paciente.

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