Virus del Sarampión para el tratamiento del cáncer

  1. Javier Albendea Roch 1
  2. Alicia Moreno Gallego 1
  3. Blanca Ongil García 1
  4. Marta Pérez Martín 1
  5. Lourdes Lledó García dir. 1
  1. 1 Universidad de Alcalá
    info

    Universidad de Alcalá

    Alcalá de Henares, España

    ROR https://ror.org/04pmn0e78

Book:
Experiencia de innovación docente 2: colección de revisiones de enfermedades infecciosas emergentes y reemergentes
  1. Cuadros González, Juan (dir.)
  2. Gegúndez Cámara, María Isabel (dir.)
  3. Florido Calleja, María Jesús (ed. lit.)
  4. Consuelo Giménez Pardo (dir.)
  5. María Rosario González Palacios (dir.)
  6. Lourdes Lledó García (dir.)
  7. Juan Romanyk (dir.)
  8. José Vicente Saz Pérez (dir.)

Publisher: Editorial Universidad de Alcalá ; Universidad de Alcalá

ISBN: 9788416599493

Year of publication: 2017

Pages: 101-114

Type: Book chapter

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Abstract

Antitumoral virotherapy means the use of attenuated strains of different kind of virus, measles virus in this case, to attack different kinds of cancers. This is a very new and promising field of research. Measles virus is very prevalent in our society, in fact a very high percentage of the population has been even vaccinated against it or infected, so there´s a very high immunity. This brings a huge advantage avoiding transmission from the security point of view. Also, through genetic engineering it´s possible the modification of wild measles virus strains to enhance tumor cells selectivity, causing no harm on normal tissues, while evading antiviral human immunity. For now, this research field is still being developed, but it offers many possibilities in no small cells lung cancer, ovarian cancer, pleural mesothelioma, cholangyocarcinoma, glioblastoma and multiple myeloma.

Data source: Dialnet