La nefrocalcinosisuna patología no tan infrecuente

  1. Clara Cotón Batres 1
  2. Morán Magro, M.
  3. Eduardo M. Bosch Fernández 1
  4. Alba Benito Salmerón 1
  5. Nerea Begoña Boldoba 1
  6. Gabriel de Arriba de la Fuente 2
  1. 1 Hospital Universitario de Guadalajara
    info

    Hospital Universitario de Guadalajara

    Guadalajara, España

    ROR https://ror.org/00jkz9152

  2. 2 Universidad de Alcalá
    info

    Universidad de Alcalá

    Alcalá de Henares, España

    ROR https://ror.org/04pmn0e78

Journal:
RIECS: Revista de Investigación y Educación en Ciencias de la Salud

ISSN: 2530-2787

Year of publication: 2024

Issue Title: La coagulopatía que dió origen a “la enfermedad real”

Volume: 9

Issue: 1

Pages: 25-33

Type: Article

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More publications in: RIECS: Revista de Investigación y Educación en Ciencias de la Salud

Abstract

La nefrocalcinosis es una entidad de prevalencia desconocida que se ha relacionado con múltiples enfermedades genéticas, alteraciones metabólicas, fármacos y la aparición de daño renal progresivo. Se caracteriza por la presencia de depósitos de calcio, ya sea de oxalato cálcico o fosfato cálcico, que se presentan de manera focal o difusa a nivel de la médula renal. El diagnóstico se realiza mediante pruebas de imagen. El mecanismo por el que se forman los depósitos cálcicos aún se encuentra en estudio, aunque generalmente se relaciona con alteraciones del metabolismo fosfo-cálcico, hipercalciuria, hiperfosfaturia o hipocitraturia, aunque existen otras patologías por las cuales la génesis de producción no es conocida. El objetivo principal de esta revisión es analizar las causas etiopatogénicas más comunes involucradas en el desarrollo de la nefrocalcinosis, así como el cuadro clínico que conforman. No obstante, son necesarios más estudios para aclarar de manera completa de esta entidad.

Bibliographic References

  • Vaidya SR, Yarrarapu SNS, Aeddula NR. Nephrocalcinosis. Radiology Illustrated: Uroradiology (Second Edition) [Internet]. 2023 Aug 8 [cited 2023 Nov 3];9783642053221:527–49. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537205/
  • Markowitz GS, Nasr SH, Klein P, Anderson H, Stack JI, Alterman L, et al. Renal failure due to acute nephrocalcinosis following oral sodium phosphate bowel cleansing. Hum Pathol. 2004 Jun;35(6):675–84.
  • Simancas-Escorcia V, Berdal A, Díaz-Caballero A. Caracterización fenotípica del síndrome amelogénesis imperfecta–nefrocalcinosis: una revisión. Duazary. 2019 Jan 1;16(1):129.
  • Priante G, Ceol M, Terrin L, Gianesello L, Quaggio F, Prete D Del, et al. Understanding the Pathophysiology of Nephrocalcinosis. In: Updates and Advances in Nephrolithiasis - Pathophysiology, Genetics, and Treatment Modalities. InTech; 2017.
  • Shavit L, Jaeger P, Unwin RJ. What is nephrocalcinosis? Vol. 88, Kidney International. Nature Publishing Group; 2015. p. 35–43.
  • Nephrocalcinosis - UpToDate [Internet]. [cited 2023 Oct 30]. Available from: https://www-uptodate-com.sescam.a17.csinet.es/contents/nephrocalcinosis?source=history_widget
  • Evan A, Lingeman J, Coe FL, Worcester E. Randall’s plaque: Pathogenesis and role in calcium oxalate nephrolithiasis. Vol. 69, Kidney International. 2006. p. 1313–8.
  • Wrong O. Nephrocalcinosis. Cameron Stewart, Davison. Alex M., Grünfeld J, editors. Vol. Clinical Nephrology. Oxford University Press; 2005. 1357–1376 p.
  • Oliveira B, Robert Kleta X, Bockenhauer D, Walsh SB. Genetic, pathophysiological, and clinical aspects of nephrocalcinosis. Am J Physiol Renal Physiol [Internet]. 2016; 311:1243–52. Available from: http://www.ajprenal.org
  • Howles SA, Thakker R V. Genetics of kidney stone disease. Vol. 17, Nature Reviews Urology. Nature Research; 2020. p. 407–21.
  • Chen A, Ro H, Mundra VRR, Joseph K, Brenner D, Carpenter TO, et al. Description of 5 Novel SLC34A3/NPT2c Mutations Causing Hereditary Hypophosphatemic Rickets With Hypercalciuria. Kidney Int Rep. 2019 Aug 1;4(8):1179–86.
  • Kim YG, Kim B, Kim MK, Chung SJ, Han HJ, Ryu JA, et al. Rapid Communication Medullary nephrocalcinosis associated with long-term furosemide abuse in adults.
  • Gonlusen G, Akgun H, Ertan A, Olivero J, Luan;, Truong D. Renal Failure and Nephrocalcinosis Associated With Oral Sodium Phosphate Bowel Cleansing Clinical Patterns and Renal Biopsy Findings. Vol. 130, Arch Pathol Lab Med. 2006.
  • Sayer JA, Carr G, Simmons NL. Nephrocalcinosis: molecular insights into calcium precipitation within the kidney. Vol. 106, Clinical Science. 2004.
  • Halbritter J, Baum M, Hynes A. Fourteen monogenic genes account for 15% of nephrolithiasis/nephrocalcinosis. Vol. 193, Journal of Urology. Elsevier Inc.; 2015. p. 2008–10.
  • Singh P, Harris PC, Sas DJ, Lieske JC. The genetics of kidney stone disease and nephrocalcinosis. Vol. 18, Nature Reviews Nephrology. Nature Research; 2022. p. 224–40.
  • Bhojani N, Paonessa JE, Hameed TA, Worcester EM, Evan AP, Coe FL, et al. Nephrocalcinosis in Calcium Stone Formers Who Do Not have Systemic Disease. Journal of Urology. 2015 Nov 1;194(5):1308–12.
  • Guignard JP, Iacobelli S. Use of diuretics in the neonatal period. Available from: https://doi.org/10.1007/s00467-021-04921-3
  • Fayard J, Pradat P, Lorthois S, Bacchetta J, Picaud JC. Nephrocalcinosis in very low birth weight infants: incidence, associated factors, and natural course. Pediatric Nephrology. 2022 Dec 1;37(12):3093–104.
  • Joung J, Cho H. Etiology and prognosis of nephrocalcinosis according to gestational age in Korean children. BMC Pediatr. 2023 Dec 1;23(1).
  • Barnett SM, Jackson AH, Rosen BA, Garb JL, Braden GL. Nephrolithiasis and Nephrocalcinosis From Topiramate Therapy in Children With Epilepsy. Kidney Int Rep. 2018 May 1;3(3):684–90.
  • Sighinolfi MC, Eissa A, Bevilacqua L, Zoeir A, Ciarlariello S, Morini E, et al. Drug-Induced Urolithiasis in Pediatric Patients. Pediatric Drugs [Internet]. 2019 Oct 20 [cited 2023 Nov 3];21(5):323–44. Available from: http://link.springer.com/10.1007/s40272-019-00355-5
  • Lava SAG, Zollinger C, Chehade H, Schaffner D, Sekarski N, Di Bernardo S. Diuretics in pediatrics. Vol. 182, European Journal of Pediatrics. Springer Science and Business Media Deutschland GmbH; 2023. p. 2077–88.
  • Madihi Y, Mostofizadeh N, Shamsipour Dehkordi H, Riahinezhad M, Hovsepian S, Rostampour N, et al. Prevalence of nephrocalcinosis in children with congenital adrenal hyperplasia. Journal of Research in Medical Sciences. 2022;27(1).
  • Aldana JC, Rodríguez LC, Bastidas N, Vásquez A. Radiological features of nephrocalcinosis, a common but forgotten entity. Vol. 96, British Journal of Radiology. British Institute of Radiology; 2023.
  • En La E, Renal E, Pantoja Pérez J, Del M, Collantes Mateos R, Haridian R, et al. Edición del Grupo Editorial Nefrología de la Sociedad Española de Nefrología. 2021;
  • Faubel S, Patel NU, Lockhart ME, Cadnapaphornchai MA. Renal Relevant Radiology: Use of Ultrasonography in Patients with AKI. Clin J Am Soc Nephrol [Internet]. 2014 Feb 2 [cited 2024 Mar 27];9(2):382. Available from: /pmc/articles/PMC3913238/
  • Assimos DG, Assimos DG. Re: Nephrolithiasis and Nephrocalcinosis from Topiramate Therapy in Children with Epilepsy. J Urol. 2018;200(5):940.
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