Neoplasia endocrina múltiple

  1. Eider Pascual Corrales 1
  2. Marta Araujo Castro 1
  3. Andrés Ortiz Flores 2
  4. Héctor Francisco Escobar Morreale 3
  1. 1 Servicio de Endocrinología y Nutrición, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Biomédica (IRYCIS), Madrid, España
  2. 2 Servicio de Endocrinología y Nutrición, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Biomédica (IRYCIS), Madrid, España. Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España
  3. 3 Servicio de Endocrinología y Nutrición, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Biomédica (IRYCIS), Madrid, España. Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España. Facultad de Medicina, Universidad de Alcalá, Alcalá de Henares, Madrid, España
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Revue:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Année de publication: 2024

Titre de la publication: Enfermedades endocrinológicas y metabólicas (I) Patología suprarrenal

Serie: 14

Número: 13

Pages: 738-749

Type: Article

DOI: 10.1016/J.MED.2024.06.013 DIALNET GOOGLE SCHOLAR

D'autres publications dans: Medicine: Programa de Formación Médica Continuada Acreditado

Résumé

Multiple endocrine neoplasia (MEN) syndromes encompass a heterogeneous group of inherited disorders characterized by a genetic predisposition to developing tumors that mainly affect the endocrine glands. The four recognized syndromes (MEN1, MEN2A, MEN2B, and MEN4) are of autosomal dominant inheritance and are phenotypically distinguished by the development of synchronous or metachronous tumors with varied clinical presentations. Knowing the genetics and progression of each syndrome is useful for determining the tumor detection time frame. Treatments for each manifestation depend on the location, risk of malignancy or recurrence, excess hormones, and surgical morbidity; they require multidisciplinary management.

Références bibliographiques

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La source de données: Dialnet