Efficacy of Pulmonary Rehabilitation in Post-COVID-19: A Systematic Review and Meta-Analysis

  1. Erika Meléndez-Oliva 123
  2. Oliver Martínez-Pozas 234
  3. Juan Nicolás Cuenca-Zaldívar 2567
  4. Jorge Hugo Villafañe 8
  5. Laura Jiménez-Ortega 910
  6. Eleuterio A. Sánchez-Romero 223
  1. 1 Universidad Europea de Valencia
    info

    Universidad Europea de Valencia

    Valencia, España

  2. 2 Universidad Europea de Madrid
    info

    Universidad Europea de Madrid

    Madrid, España

    ROR https://ror.org/04dp46240

  3. 3 Physiotherapy and Orofacial Pain Working Group, Sociedad Española de Disfunción Craneomandibular yDolor Orofacial (SEDCYDO), 28009 Madrid, Spain
  4. 4 Universidad Rey Juan Carlos
    info

    Universidad Rey Juan Carlos

    Madrid, España

    ROR https://ror.org/01v5cv687

  5. 5 Universidad de Alcalá
    info

    Universidad de Alcalá

    Alcalá de Henares, España

    ROR https://ror.org/04pmn0e78

  6. 6 Hospital Universitario Puerta de Hierro
    info

    Hospital Universitario Puerta de Hierro

    Madrid, España

    ROR https://ror.org/01e57nb43

  7. 7 Physical Therapy Unit, Primary Health Care Center “El Abajón”, 28231 Madrid, Spain
  8. 8 IRCCS Fondazione Don Carlo Gnocchi, 20148 Milan, Italy
  9. 9 Universidad Complutense de Madrid
    info

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

  10. 10 Center of Human Evolution and Behavior, Carlos III Health Institute, Complutense University of Madrid,28040 Madrid, Spain
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Libro:
Latest Research in Post-COVID (Long COVID): Pathological and Treatment Studies of Sequelae and Complications

Editorial: MDPI - Multidisciplinary Digital Publishing Institute

ISBN: 978-3-7258-1505-0,  978-3-7258-1506-7

Año de publicación: 2024

Páginas: 79-102

Tipo: Capítulo de Libro

DOI: 10.3390/BOOKS978-3-7258-1506-7 GOOGLE SCHOLAR lock_openAcceso abierto editor

Resumen

This systematic review and meta-analysis examines how pulmonary rehabilitation impacts in patients suffering from subacute and long COVID-19 infections, gaugingenhancements in of dyspnea, physical function, quality of life, psychological state (anxiety anddepression), and fatigue. Methods: Three electronic databases (PubMed, Web of Science, CochraneLibrary) were systematically searched for full-text articles published from inception to January 2023.Randomized, quasi-experimental, and observational studies were included, with adults diagnosedwith subacute or long COVID-19 who received pulmonary rehabilitation as intervention. Outcomesrelated to dyspnea, physical function, quality of life, fatigue, and psychological status were included.Risk of bias was assessed with Cochrane Risk of Bias Tool for Randomized Controlled Trials andRisk of bias in non-randomized studies of intervention. The review was registered before starting inPROSPERO (CRD: 42022373075). Results: Thirty-four studies were included, involving 1970 patientswith subacute and long COVID-19. The meta-analysis demonstrated moderate to large effects ondyspnea, physical function, quality of life, and depressive symptoms compared to usual care intervention. No significant differences were found in fatigue compared to usual care, nor in anxiety levelsafter pulmonary rehabilitation intervention. Conclusions: Pulmonary rehabilitation has the potentialto improve health outcomes in patients with subacute and long COVID-19. However, due to the highrisk of bias of included studies, conclusions should be taken with caution

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