Mecanismos moleculares implicados en cáncer: transducción de señales, epigenetica y metabolismo ; Molecular mechanisms involved in cáncer: signal transduction, epigenetics and metabolism
TRAEME
Centro Nacional de Investigaciones Oncológicas
Madrid, EspañaPublicacions en col·laboració amb investigadors/es de Centro Nacional de Investigaciones Oncológicas (40)
2016
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Cancer detection and prognosis
Nucleic Acid Testing for Human Disease (CRC Press), pp. 353-371
2012
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A DNA methylation fingerprint of 1628 human samples
Genome Research, Vol. 22, Núm. 2, pp. 407-419
2010
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A genetic defect in exportin-5 traps precursor MicroRNAs in the nucleus of cancer cells
Cancer Cell, Vol. 18, Núm. 4, pp. 303-315
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BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors
Journal of Clinical Oncology
2009
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A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
Nature Genetics, Vol. 41, Núm. 3, pp. 365-370
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Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity
Oncogene, Vol. 28, Núm. 11, pp. 1477-1484
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Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
Oncogene, Vol. 28, Núm. 6, pp. 781-791
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The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer
Genome Research, Vol. 19, Núm. 3, pp. 438-451
2008
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A microRNA DNA methylation signature for human cancer metastasis
Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Núm. 36, pp. 13556-13561
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Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer
American Journal of Clinical Pathology, Vol. 130, Núm. 3, pp. 414-424
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Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies
Cancer Research, Vol. 68, Núm. 11, pp. 4116-4122
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Epigenetics and Cancer: DNA Methylation
Epigenetics in Biology and Medicine (CRC Press), pp. 3-16
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Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma
BJU International, Vol. 102, Núm. 6, pp. 747-755
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Reply to "HDAC2 deficiency and histone acetylation"
Nature Genetics
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Transforming pathways unleashed by a HDAC2 mutation in human cancer
Oncogene, Vol. 27, Núm. 28, pp. 4008-4012
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Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins
Oncogene, Vol. 27, Núm. 25, pp. 3556-3566
2007
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Combinatorial effects of splice variants modulate function of Aiolos
Journal of Cell Science, Vol. 120, Núm. 15, pp. 2619-2630
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Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells
Cancer Research, Vol. 67, Núm. 24, pp. 11481-11486
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EGF prevents the neuroendocrine differentiation of LNCaP cells induced by serum deprivation: The modulator role of PI3K/Akt
Neoplasia
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Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
Nucleic Acids Research, Vol. 35, Núm. 7, pp. 2191-2198