
Alejandro
Romero Martínez
Publications by the researcher in collaboration with Alejandro Romero Martínez (10)
2020
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
2019
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Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy
Molecules, Vol. 24, Núm. 8
2017
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5-Methyl-: N -(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5 H -indolo[2,3- b] quinolin-11-amine: A highly potent human cholinesterase inhibitor
MedChemComm, Vol. 8, Núm. 6, pp. 1307-1317
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Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases
Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12765-12769
2016
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The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators
Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9967-9973
2015
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Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease
Mini-Reviews in Medicinal Chemistry, Vol. 15, Núm. 8, pp. 648-658
2014
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Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561
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Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234
CNS Neuroscience and Therapeutics
2012
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Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763
2010
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Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives
Journal of Medicinal Chemistry, Vol. 53, Núm. 14, pp. 5129-5143