Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
DISCOBAC
Universidad Camilo José Cela
Villanueva de la Cañada, España
Publications en collaboration avec des chercheurs de Universidad Camilo José Cela (11)
2025
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Generation and validation of a novel multitarget small molecule in glioblastoma
Cell Death and Disease, Vol. 16, Núm. 1
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N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer's disease
Biomedicine and Pharmacotherapy, Vol. 192
2022
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Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment
Antioxidants, Vol. 11, Núm. 9
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Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes
Antioxidants, Vol. 11, Núm. 8
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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents
ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1097-1108
2021
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Studies on the affinity of 6-[(: N -(cyclo)aminoalkyl)oxy]-4 H -chromen-4-ones for sigma 1/2 receptors
RSC Medicinal Chemistry, Vol. 12, Núm. 6, pp. 1000-1004
2020
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Acetylcholinesterase inhibition of diversely functionalized quinolinones for alzheimer’s disease therapy
International Journal of Molecular Sciences, Vol. 21, Núm. 11, pp. 1-20
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Automated Synthesis of New Quinoxalinetacrines
ChemistrySelect, Vol. 5, Núm. 21, pp. 6491-6493
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Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
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Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
Scientific Reports, Vol. 10, Núm. 1