Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
DISCOBAC
Universidad Complutense de Madrid
Madrid, España
Publications en collaboration avec des chercheurs de Universidad Complutense de Madrid (14)
2025
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Copper-mediated divergent reactivity of allene-tethered carbamates under radical conditions
Organic Letters, Vol. 27, Núm. 25, pp. 6823-6829
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N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer's disease
Biomedicine and Pharmacotherapy, Vol. 192
2024
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Ni(2,2′:6′,2′′-terpyridine)2: a high-spin octahedral formal Ni(0) complex
Dalton Transactions, Vol. 53, Núm. 20, pp. 8550-8554
2023
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Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates
Journal of Organic Chemistry, Vol. 88, Núm. 11, pp. 7373-7380
2022
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Superparamagnetic Iron Oxide Nanoparticles Decorated Mesoporous Silica Nanosystem for Combined Antibiofilm Therapy
Pharmaceutics, Vol. 14, Núm. 1
2021
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Emerging Strategies in Anticancer Combination Therapy Employing Silica-Based Nanosystems
Biotechnology Journal, Vol. 16, Núm. 3
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Pd-catalyzed C(sp3)-C(sp) bond formation in iodocyclobutenes
Chemical Communications, Vol. 57, Núm. 68, pp. 8456-8459
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Recent advances toward the use of mesoporous silica nanoparticles for the treatment of bacterial infections
International Journal of Nanomedicine, Vol. 16, pp. 4409-4430
2020
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Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
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Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
Scientific Reports, Vol. 10, Núm. 1
2019
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Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489
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Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy
Molecules, Vol. 24, Núm. 8
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Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones
Bioorganic Chemistry, Vol. 86, pp. 445-451