Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
DISCOBAC


Universidad Autónoma de Madrid
Madrid, EspañaPublications in collaboration with researchers from Universidad Autónoma de Madrid (32)
2024
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Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555
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Contilistat, a New Multitarget Small Polyfunctionalized Indole Derivative
Synlett
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Ni(2,2′:6′,2′′-terpyridine)2: a high-spin octahedral formal Ni(0) complex
Dalton Transactions, Vol. 53, Núm. 20, pp. 8550-8554
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Nickel-Catalyzed Cycloisomerization of 1,5-Allenynes
Advanced Synthesis and Catalysis, Vol. 366, Núm. 4, pp. 790-797
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Synthesis of Ladderanes by Nickel-Catalyzed Cyclodimerization of Allenynes: Scope and Mechanism
Advanced Synthesis and Catalysis, Vol. 366, Núm. 22, pp. 4755-4764
2023
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METAL-CATALYZED BORYLATIVE CYCLIZATION REACTIONS OF POLYUNSATURATED SUBSTRATES FOR THE SYNTHESIS OF HETEROCYCLES
Targets in Heterocyclic Systems, Vol. 27, pp. 309-340
2022
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Nickel-Catalyzed Hydroborylative Polycyclization of Allenynes: an Atom-Economical and Diastereoselective Synthesis of Bicyclic 5-5 Fused Rings
Advanced Synthesis and Catalysis, Vol. 364, Núm. 10, pp. 1716-1723
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Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment
Antioxidants, Vol. 11, Núm. 9
2021
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On the mechanism of the formation of alkyl-Ni(i) catalysts
Chemical Communications, Vol. 57, Núm. 19, pp. 2424-2427
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Pd-catalyzed C(sp3)-C(sp) bond formation in iodocyclobutenes
Chemical Communications, Vol. 57, Núm. 68, pp. 8456-8459
2020
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
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Regioselective Iron-Catalysed Cross-Coupling Reaction of Aryl Propargylic Bromides and Aryl Grignard Reagents
Advanced Synthesis and Catalysis, Vol. 362, Núm. 1, pp. 146-151
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Triflyl-assisted reductive Pd-catalyzed Tsuji-Trost type reaction
Chemical Communications, Vol. 56, Núm. 45, pp. 6070-6073
2019
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Atom-Economical Ni-Catalyzed Diborylative Cyclization of Enynes: Preparation of Unsymmetrical Diboronates
Organic Letters, Vol. 21, Núm. 16, pp. 6552-6556
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Atom-economical regioselective Ni-catalyzed hydroborylative cyclization of enynes: Development and mechanism
Catalysis Science and Technology, Vol. 9, Núm. 4, pp. 1021-1029
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Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489
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Metal- A nd Photocatalysis to Gain Regiocontrol and Stereodivergence in Hydroarylations of Unsymmetrical Dialkyl Alkynes
ACS Catalysis, Vol. 9, Núm. 11, pp. 10567-10574
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New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition
Journal of Medicinal Chemistry, Vol. 62, Núm. 24, pp. 11416-11422
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Ni-Catalyzed Cyclization of Enynes and Alkynylboronates: Atom-Economical Synthesis of Boryl-1,4-dienes
Chemistry - A European Journal, Vol. 25, Núm. 64, pp. 14512-14516
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Ni-Catalyzed Reductive Dicarbofunctionalization of Nonactivated Alkenes: Scope and Mechanistic Insights
Journal of the American Chemical Society, Vol. 141, Núm. 35, pp. 13812-13821