DISCOBAC
Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
Publications (95)
2025
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2-{N-[ω-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for σ1/2 Receptors
International Journal of Molecular Sciences, Vol. 26, Núm. 3
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Chiral Transition Metal Complexes Featuring Limonene-Derived Ligands: Roles in Catalysis and Biology
Inorganics, Vol. 13, Núm. 10
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Contilistat, a New Multitarget Small Polyfunctionalized Indole Derivative
Synlett, Vol. 36, Núm. 16, pp. 2655-2660
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Copper-mediated divergent reactivity of allene-tethered carbamates under radical conditions
Organic Letters, Vol. 27, Núm. 25, pp. 6823-6829
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Exploring SAR insights into royleanones for P-gp modulation
Biomedicine and Pharmacotherapy, Vol. 185
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Exploring the Impact of Phenanthroline-Based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis-Related Processes
Chemistry - A European Journal, Vol. 31, Núm. 41
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Functionalised gold nanoparticles using abietane diterpenoids from Plectranthus grandidentatus Gürke for cancer therapy
Journal of Drug Delivery Science and Technology, Vol. 114
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Generation and validation of a novel multitarget small molecule in glioblastoma
Cell Death and Disease, Vol. 16, Núm. 1
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Microbubble synthesis of hybridised bacterial cellulose-gelatin separators for multifunctional supercapacitors
Sustainable Energy and Fuels, Vol. 9, Núm. 7, pp. 1745-1754
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Multicomponent Synthesis of Multi-Target Quinazolines Modulating Cholinesterase, Oxidative Stress, and Amyloid Aggregation Activities for the Therapy of Alzheimer’s Disease
Molecules, Vol. 30, Núm. 19
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N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer's disease
Biomedicine and Pharmacotherapy, Vol. 192
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NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin-Binding Integrins
Advanced Science, Vol. 12, Núm. 20
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Plectranthus amboinicus: A Systematic Review of Traditional Uses, Phytochemical Properties, and Therapeutic Applications
Pharmaceuticals, Vol. 18, Núm. 5
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Structural basis of topoisomerase targeting by delafloxacin
Nature Communications , Vol. 16, Núm. 1
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Síntesis racional de inhibidores de la enzima HDAC6 para el tratamiento del Alzheimer
Dianas: revista de dianas terapéuticas, Vol. 14, Núm. 2
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Zervimesine, a Small Sigma-2 Receptor Selective Modulator for Alzheimer’s Disease
ACS Medicinal Chemistry Letters
2024
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Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases
Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555
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Cs2CO3-Promoted Alkylation of 3-Cyano-2(1H)-Pyridones: Anticancer Evaluation and Molecular Docking
ChemPlusChem, Vol. 89, Núm. 9
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DNA Interactions and Biological Activity of 2,9-Disubstituted 1,10-Phenanthroline Thiosemicarbazone-Based Ligands and a 4-Phenylthiazole Derivative
Biology, Vol. 13, Núm. 1
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Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors
ACS Chemical Neuroscience, Vol. 15, Núm. 18, pp. 3363-3383