Mecanismo de acción de moléculas con actividad biológica ; Mechanisms of action of biolocally active compounds
Moabac
Universidad Europea de Madrid
Madrid, EspañaPublicaciones en colaboración con investigadores/as de Universidad Europea de Madrid (8)
2020
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Distinct binding of cetirizine enantiomers to human serum albumin and the human histamine receptor H1
Journal of Computer-Aided Molecular Design, Vol. 34, Núm. 10, pp. 1045-1062
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N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs
Frontiers in Bioengineering and Biotechnology, Vol. 8
2019
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All-atom catalytic cycle of Lactobacillus nucleoside 2’-deoxyribosyltransferases
BIOTRANS 2019
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Reaction mechanism of nucleoside 2′-deoxyribosyltransferases: Free-energy landscape supports an oxocarbenium ion as the reaction intermediate
Organic and Biomolecular Chemistry, Vol. 17, Núm. 34, pp. 7891-7899
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Structure-Guided Tuning of a Selectivity Switch towards Ribonucleosides in Trypanosoma brucei Purine Nucleoside 2′-Deoxyribosyltransferase
ChemBioChem, Vol. 20, Núm. 24, pp. 2996-3000
2018
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Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis
Applied Microbiology and Biotechnology, Vol. 102, Núm. 16, pp. 6947-6957
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Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2’-DeoxyribosylTransferase from Trypanosoma brucei
ChemCatChem, Vol. 10, Núm. 19, pp. 4406-4416
2017
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2′-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases
Applied Microbiology and Biotechnology, Vol. 101, Núm. 19, pp. 7187-7200