Mecanismo de acción de moléculas con actividad biológica ; Mechanisms of action of biolocally active compounds
Moabac
Ghent University
Gante, BélgicaPublicaciones en colaboración con investigadores/as de Ghent University (5)
2023
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Chemical modulation of microtubule structure through the laulimalide/peloruside site
Structure, Vol. 31, Núm. 1, pp. 88-99.e5
2011
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Synthesis, modeling and evaluation of 3′-(1-aryl-1H-tetrazol-5- ylamino)-substituted 3′-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors
Organic and Biomolecular Chemistry, Vol. 9, Núm. 3, pp. 892-901
2010
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3′-[4-Aryl-(1,2,3-triazol-1-yl)]-3′-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase
Journal of Medicinal Chemistry, Vol. 53, Núm. 7, pp. 2902-2912
2009
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Human mitochondrial thymidine kinase is selectively inhibited by 3′-thiourea derivatives of β-thymidine: Identification of residues crucial for both inhibition and catalytic activity
Molecular Pharmacology, Vol. 75, Núm. 5, pp. 1127-1136
2006
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Mutational pathways, resistance profile, and side effects of cyanovirin relative to human immunodeficiency virus type 1 strains with N-glycan deletions in their gp120 envelopes
Journal of Virology, Vol. 80, Núm. 17, pp. 8411-8421