Moabac
Mecanismo de acción de moléculas con actividad biológica - Mechanisms of action of biolocally active compounds
Publications (61) Publications in which a researcher has participated
2024
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A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria
Nature Communications, Vol. 15, Núm. 1
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Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage ϕ29
Nucleic Acids Research, Vol. 52, Núm. 4, pp. 2045-2065
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The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 39, Núm. 1
2023
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Alternative Approaches to Understand Microtubule Cap Morphology and Function
ACS Omega, Vol. 8, Núm. 4, pp. 3540-3550
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Chemical modulation of microtubule structure through the laulimalide/peloruside site
Structure, Vol. 31, Núm. 1, pp. 88-99.e5
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Computational Approaches to Enzyme Inhibition by Marine Natural Products in the Search for New Drugs
Marine Drugs, Vol. 21, Núm. 2
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Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates
International Journal of Molecular Sciences, Vol. 24, Núm. 4
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Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
European Journal of Medicinal Chemistry, Vol. 259
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Molecular basis of the final step of cell division in Streptococcus pneumoniae
Cell Reports, Vol. 42, Núm. 7
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Next generation of selenocyanate and diselenides with upgraded leishmanicidal activity
Bioorganic Chemistry, Vol. 138
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Structural insight into the stabilization of microtubules by taxanes
eLife, Vol. 12
2022
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A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro
Pharmaceuticals, Vol. 15, Núm. 8
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Evaluation of new Toxocara canis chimeric antigens as an alternative to conventional TES-Ag for anti-Toxocara antibodies detection
Heliyon, Vol. 8, Núm. 10
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Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity
European Journal of Medicinal Chemistry, Vol. 244
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Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library
European Journal of Medicinal Chemistry, Vol. 243
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Obtención y purificación de la cisteína sintasa de "L. infantum"
Dianas: revista de dianas terapéuticas, Vol. 11, Núm. 2
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Organotropic dendrons with high potency as HIV-1, HIV-2 and EV-A71 cell entry inhibitors
European Journal of Medicinal Chemistry, Vol. 237
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Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase
European Journal of Medicinal Chemistry, Vol. 227
2021
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3,5-Dimethyl-4-isoxazoyl selenocyanate as promising agent for the treatment of Leishmania infantum-infected mice
Acta Tropica, Vol. 215
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Double Arylation of the Indole Side Chain of Tri- And Tetrapodal Tryptophan Derivatives Renders Highly Potent HIV-1 and EV-A71 Entry Inhibitors
Journal of Medicinal Chemistry, Vol. 64, Núm. 14, pp. 10027-10046