Publicaciones en colaboración con investigadores/as de Universidad Complutense de Madrid (18)

2023

  1. Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates

    Journal of Organic Chemistry, Vol. 88, Núm. 11, pp. 7373-7380

2020

  1. Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties

    International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18

  2. Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models

    Scientific Reports, Vol. 10, Núm. 1

2019

  1. Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489

  2. Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy

    Molecules, Vol. 24, Núm. 8

  3. Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones

    Bioorganic Chemistry, Vol. 86, pp. 445-451

2018

  1. Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 155, pp. 839-846

2017

  1. 5-Methyl-: N -(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5 H -indolo[2,3- b] quinolin-11-amine: A highly potent human cholinesterase inhibitor

    MedChemComm, Vol. 8, Núm. 6, pp. 1307-1317

  2. Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

    Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12765-12769

2016

  1. Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 118, pp. 178-192

2015

  1. Pyranopyrazolotacrines as nonneurotoxic, Aβ-anti-aggregating and neuroprotective agents for Alzheimer's disease

    Future Medicinal Chemistry, Vol. 7, Núm. 7, pp. 845-855

2014

  1. Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 80, pp. 543-561

  2. Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents

    Cardiovascular Research, Vol. 104, Núm. 2, pp. 337-346

2013

  1. Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore

    Biochemical Pharmacology, Vol. 86, Núm. 2, pp. 267-278

2012

  1. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763

2006

  1. Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism

    Cardiovascular Research, Vol. 72, Núm. 1, pp. 80-89

2005

  1. Synthesis, structural and conformational study of selected N-substituted phthalimides

    Central European Journal of Chemistry, Vol. 3, Núm. 4, pp. 683-704

2003

  1. Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization

    Journal of Pharmacology and Experimental Therapeutics, Vol. 304, Núm. 2, pp. 862-873