Publikationen, an denen er mitarbeitet Pedro Alejandro Sánchez Murcia (13)

2024

  1. The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 39, Núm. 1

2022

  1. Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity

    European Journal of Medicinal Chemistry, Vol. 244

2021

  1. Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6137-6160

2019

  1. Identification of NEK3 and MOK as novel targets for lithium

    Chemical Biology and Drug Design

  2. Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase

    ACS Infectious Diseases, Vol. 5, Núm. 6, pp. 873-891

2018

  1. Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability

    European Journal of Medicinal Chemistry, Vol. 149, pp. 238-247

2017

  1. First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#

    European Journal of Medicinal Chemistry, Vol. 135, pp. 49-59

  2. Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides

    European Journal of Medicinal Chemistry, Vol. 140, pp. 615-623

  3. Structure-based domain assignment in Leishmania infantum EndoG: Characterization of a pH-dependent regulatory switch and a C-Terminal extension that largely dictates DNA substrate preferences

    Nucleic Acids Research, Vol. 45, Núm. 15, pp. 9030-9045

2016

  1. A functional BH3 domain in an aquaporin from Leishmania infantum

    Cell Death Discovery, Vol. 2, Núm. 1

  2. Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania

    Cell Death and Disease

2015

  1. Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase

    RSC Advances, Vol. 5, Núm. 69, pp. 55784-55794

2013

  1. Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides

    ChemBioChem, Vol. 14, Núm. 10, pp. 1212-1217