Paula
Ortega Lopez
Profesor/a Titular Universidad
Hospital General Universitario Gregorio Marañón
Madrid, EspañaPublicacions en col·laboració amb investigadors/es de Hospital General Universitario Gregorio Marañón (19)
2015
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Bifunctional Chelating Agents Based on Ionic Carbosilane Dendrons with DO3A at the Focal Point and Their Complexation Behavior with Copper(II)
Inorganic Chemistry, Vol. 54, Núm. 18, pp. 8943-8956
2013
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Dendrimers in RNAi Delivery
Advanced Delivery and Therapeutic Applications of RNAi (John Wiley and Sons), pp. 163-185
2012
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Carbosilane dendrimers are a non-viral delivery system for antisense oligonucleotides: Characterization of dendriplexes
Journal of Biomedical Nanotechnology, Vol. 8, Núm. 1, pp. 57-73
2011
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Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1
Colloids and Surfaces B: Biointerfaces, Vol. 83, Núm. 2, pp. 388-391
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Erratum: Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16 (Pharmaceutical Research DOI: 10.1007/s11095-008-9776-z)
Pharmaceutical Research
2010
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Carbosilane dendrimers to transfect human astrocytes with small interfering RNA targeting human immunodeficiency virus
BioDrugs, Vol. 24, Núm. 5, pp. 331-343
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Gene therapy in HIV-infected cells to decrease viral impact by using an alternative delivery method
ChemMedChem, Vol. 5, Núm. 6, pp. 921-929
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Globular carbosilane dendrimers with mannose groups at the periphery: synthesis, characterization and toxicity in dendritic cells
Tetrahedron, Vol. 66, Núm. 18, pp. 3326-3331
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Synthesis of carbosilane dendrons and dendrimers derived from 1,3,5-trihydroxybenzene
Tetrahedron, Vol. 66, Núm. 47, pp. 9203-9213
2009
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Binding properties of water-soluble carbosilane dendrimers
Journal of Fluorescence, Vol. 19, Núm. 2, pp. 267-275
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Carbosilane dendrimers peripherally functionalized with dansyl fluorescence tags and their cellular internalization studies
Organic and Biomolecular Chemistry, Vol. 7, Núm. 15, pp. 3079-3085
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Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16
Pharmaceutical Research, Vol. 26, Núm. 3, pp. 577-586
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Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective Role for HIF-1α in early chemical hypoxia-mediated neurotoxicity
Pharmaceutical Research, Vol. 26, Núm. 5, pp. 1181-1191
2008
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Amine and ammonium functionalization of chloromethylsilane-ended dendrimers. Antimicrobial activity studies
Organic and Biomolecular Chemistry, Vol. 6, Núm. 18, pp. 3264-3269
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Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes
Journal of Controlled Release, Vol. 132, Núm. 1, pp. 55-64
2007
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Analysis of interaction between dendriplexes and bovine serum albumin
Biomacromolecules, Vol. 8, Núm. 7, pp. 2059-2062
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Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
Organic and Biomolecular Chemistry, Vol. 5, Núm. 12, pp. 1886-1893
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Water-soluble carbosilane dendrimers: Synthesis biocompatibility and complexation with oligonucleotides; evaluation for medical applications
Chemistry - A European Journal, Vol. 13, Núm. 2, pp. 483-495
2006
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Novel water-soluble carbosilane dendrimers: Synthesis and biocompatibility
European Journal of Inorganic Chemistry, pp. 1388-1396