Publicaciones (21) Publicaciones de Alicia Mansilla Aparicio

2023

  1. The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Gα chaperone and GEF Ric-8A

    eLife, Vol. 12

2022

  1. The inhibition of NCS-1 binding to Ric8a rescues fragile X syndrome mice model phenotypes

    Frontiers in Neuroscience, Vol. 16

  2. Tools and Biomarkers for the Study of Retinal Ganglion Cell Degeneration

    International Journal of Molecular Sciences, Vol. 23, Núm. 8

2019

  1. Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library

    Nature Communications, Vol. 10, Núm. 1

2018

  1. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators

    Journal of Medicinal Chemistry, Vol. 61, Núm. 14, pp. 5910-5921

  2. Molecular mechanisms that change synapse number

    Journal of Neurogenetics, Vol. 32, Núm. 3, pp. 155-170

2017

  1. Interference of the complex between NCS-1 & Ric8a with phenothiazines regulates synaptic function & is an approach for fragile X syndrome

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Núm. 6, pp. E999-E1008

2016

  1. Ligand-independent requirements of steroid receptors EcR and USP for cell survival

    Cell Death and Differentiation, Vol. 23, Núm. 3, pp. 405-416

2014

  1. A new overgrowth syndrome is due to mutations in RNF125

    Human Mutation, Vol. 35, Núm. 12, pp. 1436-1441

  2. Frq2 from Drosophila melanogaster: Cloning, expression, purification, crystallization and preliminary X-ray analysis

    Acta Crystallographica Section F:Structural Biology Communications, Vol. 70, Núm. 4, pp. 530-534

  3. The guanine-exchange factor Ric8a binds to the Ca2+ sensor NCS-1 to regulate synapse number and neurotransmitter release

    Journal of Cell Science, Vol. 127, Núm. 19, pp. 4246-4259

2011

  1. Isoform-specific regulation of a steroid hormone nuclear receptor by an E3 ubiquitin ligase in Drosophila melanogaster

    Genetics, Vol. 189, Núm. 3, pp. 871-883

  2. The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity

    Cell Death and Disease, Vol. 2, Núm. 8

2009

  1. Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

    Molecular Cell, Vol. 33, Núm. 4, pp. 517-527

  2. Troponin I and Tropomyosin regulate chromosomal stability and cell polarity

    Journal of Cell Science, Vol. 122, Núm. 15, pp. 2623-2631

2008

  1. Evolution of the insulin receptor family and receptor isoform expression in vertebrates

    Molecular Biology and Evolution, Vol. 25, Núm. 6, pp. 1043-1053

2006

  1. Proinsulin in development: New roles for an ancient prohormone

    Diabetologia, Vol. 49, Núm. 6, pp. 1142-1150

  2. The regulated expression of chimeric tyrosine hydroxylase-insulin transcripts during early development

    Nucleic Acids Research, Vol. 34, Núm. 12, pp. 3455-3464

  3. ¿Qué sabemos de la función de la proinsulina en la vida embrionaria?

    Endocrinologia y Nutricion

2005

  1. Developmental regulation of a proinsulin messenger RNA generated by intron retention

    EMBO Reports, Vol. 6, Núm. 12, pp. 1182-1187