Biología de Sistemas
Departamento
![Foto de Enrique](/img/nophoto.png)
Enrique
de la Rosa Cano
Publicaciones en las que colabora con Enrique de la Rosa Cano (16)
2023
2022
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Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
Cell Death and Disease, Vol. 13, Núm. 4
2021
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Tlr2 gene deletion delays retinal degeneration in two genetically distinct mouse models of retinitis pigmentosa
International Journal of Molecular Sciences, Vol. 22, Núm. 15
2018
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Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa
Molecular Neurodegeneration, Vol. 13, Núm. 1
2016
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Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina
Scientific Reports, Vol. 6
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Intravitreal injection of proinsulin-loaded microspheres delays photoreceptor cell death and vision loss in the rd10 mouse model of retinitis pigmentosa
Investigative Ophthalmology and Visual Science, Vol. 57, Núm. 8, pp. 3610-3618
2013
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Balance between autophagic pathways preserves retinal homeostasis
Aging Cell, Vol. 12, Núm. 3, pp. 478-488
2012
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Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa
Human Gene Therapy, Vol. 23, Núm. 12, pp. 1290-1300
2008
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Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa
Investigative Ophthalmology and Visual Science, Vol. 49, Núm. 9, pp. 4188-4194
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Functional and structural modifications during retinal degeneration in the rd10 mouse
Neuroscience, Vol. 155, Núm. 3, pp. 698-713
2006
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Proinsulin in development: New roles for an ancient prohormone
Diabetologia, Vol. 49, Núm. 6, pp. 1142-1150
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Proinsulin/insulin is synthesized locally and prevents caspase- and cathepsin-mediated cell death in the embryonic mouse retina
Journal of Neurochemistry, Vol. 99, Núm. 2, pp. 524-536
2005
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Developmental regulation of a proinsulin messenger RNA generated by intron retention
EMBO Reports, Vol. 6, Núm. 12, pp. 1182-1187
2003
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Functional modifications in rod bipolar cells in a mouse model of retinitis pigmentosa
Vision Research
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Upstream AUGs in embryonic proinsulin mRNA control its low translation level
EMBO Journal, Vol. 22, Núm. 20, pp. 5582-5592