Publicacións nas que colabora con Claire Coderch Boué (12)

2014

  1. Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases

    Biochemical Journal, Vol. 458, Núm. 3, pp. 547-557

  2. Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches

    ACS Chemical Biology, Vol. 9, Núm. 4, pp. 1033-1043

  3. One-pot synthesis of vinca alkaloids-phomopsin hybrids

    Journal of Medicinal Chemistry, Vol. 57, Núm. 12, pp. 5470-5476

2013

  1. A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis

    Organic and Biomolecular Chemistry, Vol. 11, Núm. 18, pp. 3046-3056

  2. Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of TypeII Dehydroquinase Inhibitors

    ChemMedChem, Vol. 8, Núm. 5, pp. 740-747

  3. Synthesis and biological evaluation of a new series of highly functionalized 7′- homo -anhydrovinblastine derivatives

    Journal of Medicinal Chemistry, Vol. 56, Núm. 15, pp. 6088-6100

2012

  1. Comparative Binding Energy (COMBINE) Analysis Supports a Proposal for the Binding Mode of Epothilones to β-Tubulin

    ChemMedChem, Vol. 7, Núm. 5, pp. 836-843

  2. Exploración de los sitios de unión de antitumorales a la tubulina mediante herramientas computacionales y simulaciones de dinámica molecular

    Exploración de los sitios de unión de antitumorales a la tubulina mediante herramientas computacionales y simulaciones de dinámica molecular

  3. Tubulin-based structure-affinity relationships for antimitotic Vinca alkaloids

    Anti-Cancer Agents in Medicinal Chemistry, Vol. 12, Núm. 3, pp. 219-225

2011

  1. Identification of Aldo-Keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A1: Implications for antitumoral activity

    Cancer Research, Vol. 71, Núm. 12, pp. 4161-4171

  2. Mechanistic insight into the catalytic activity of ββα-metallonucleases from computer simulations: Vibrio vulnificus periplasmic nuclease as a test case

    ChemBioChem, Vol. 12, Núm. 17, pp. 2615-2622

2008

  1. Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel

    Chemistry and Biology, Vol. 15, Núm. 6, pp. 573-585