Ciencias Biomédicas
Departamento
University of Rome Tor Vergata
Roma, ItaliaPublicaciones en colaboración con investigadores/as de University of Rome Tor Vergata (6)
2006
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Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors
Journal of Virology, Vol. 80, Núm. 14, pp. 7186-7198
2005
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High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations
Journal of Virology, Vol. 79, Núm. 16, pp. 10718-10729
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The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs
FEBS Letters, Vol. 579, Núm. 11, pp. 2294-2300
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The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors
Molecular Pharmacology, Vol. 68, Núm. 1, pp. 49-60
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The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-Calanolide A
Molecular Pharmacology, Vol. 68, Núm. 3, pp. 652-659
2004
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Identification of the minimal conserved structure of HIV-1 protease in the presence and absence of drug pressure
AIDS, Vol. 18, Núm. 12, pp. 11-19