Diseño y evaluación de estrategias vacunales frente a la leishmaniosis visceral y cutáneaoptimización del candidato poliantigénico HisAK70

  1. Martinez Rodrigo, Abel
unter der Leitung von:
  1. Francisco Javier Carrión Herrero Doktorvater/Doktormutter
  2. Gustavo Domínguez Bernal Doktorvater/Doktormutter

Universität der Verteidigung: Universidad Complutense de Madrid

Fecha de defensa: 28 von Januar von 2021

Gericht:
  1. Guadalupe Miró Corrales Präsident/in
  2. María Teresa Gómez Muñoz Sekretär/in
  3. Raquel Álvarez Velilla Vocal
  4. Carla Alexandra Soares Maia Vocal
  5. Antonio Jiménez Ruiz Vocal

Art: Dissertation

Teseo: 154112 DIALNET lock_openDocta Complutense editor

Zusammenfassung

Leishmaniosis is a parasitic disease caused by different species of protozoa included in the genus Leishmania. It is classified as a neglected tropical disease, with incidence in different regions of the Mediterranean Basin and the Middle East, as well as in tropical and subtropical areas. In humans there are different clinical manifestation, depending on the Leishmania species involved, ranging from the appearance of local lesions, cutaneous leishmaniasis (CL) and mucocutaneous (MCL), to systemic involvement, visceral leishmaniasis (VL), and even death in the absence of adequate treatment. It should be noted that dogs are the main reservoir of L. infantum, the causal agent of human zoonotic VL, making it an important epidemiological agent...