Funciones efectoras de los linfocitos T

  1. Díaz Martín, David
  2. Barcenilla Rodríguez, Hugo
  3. Borrero Corte, M. José
  4. Álvarez de Mon Soto, Melchor
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2013

Issue Title: Enfermedades del sistema inmune (I): fundamentos fisiológicos

Series: 11

Issue: 28

Pages: 1742-1751

Type: Article

DOI: 10.1016/S0304-5412(13)70551-1 DIALNET GOOGLE SCHOLAR

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Abstract

We begin this chapter by describing the recirculation of T Iymphocytes and explaining how particular populations of T Iymphocytes selectively enter Iymph nodes and specific tissues, a phenomenon known as Iymphocytic accommodation or addressing. We examine in detail differentiation following an antigen encounter, specifically the three functional states of T Iymphocytes: virgin, memory and effector. We pay special attention to the effector functions of the helper and cytotoxic T Iymphocytes, as well as their differentiation into Th1, Th2 and Th17 Iymphocytes. Finally, we briefly examine the T gamma delta and NKT Iymphocytes as well as immunological memory and the shutdown of immune responses.