Sarcoidosis

  1. Revenga Martínez, M.
  2. Blázquez Cañamero, M.A.
  3. Llop Vilatella, M.
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Ano de publicación: 2017

Serie: 12

Número: 27

Páxinas: 1560-1573

Tipo: Artigo

DOI: 10.1016/J.MED.2017.02.002 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumo

Introduction Sarcoidosis is a multisystemic disease affecting young adults with slight female predominance. Usually has bilateral hilar lymphadenopathy, pulmonary infiltrates, and eye and skin lesions. From an asymptomatic state to a chronic condition, with the possibility of causing severe clinical sequelae, deterioration of the quality of life, and even death. Aetiopathogenesis Of unknown aetiopathogenesis, will suggest that the exposure to one or several antigens, environmental, infectious or genetic, triggers an abnormal immune response in a genetically susceptible host. Diagnosis Definitive diagnosis of sarcoidosis requires a compatible clinical-radiological manifestations, histological evidence of non-caseating granulomas and exclusion of other granulomatous diseases. Treatment The basis of the treatment are the corticosteroids. Immunosuppressants may be used, as savers of corticosteroids, or second-line treatment, given its ineffectiveness, side effects, or the need for prolonged treatment. And as a third option, biological agents and even organ transplant.

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Fonte de datos: Dialnet