Efectos del clorpirifós en muerte celular y especificación fenotípica en las células madre neurales humanas

  1. Andreea Stefania Rosca
  2. Raquel Coronel
  3. Isabel Liste
Book:
Octavas Jornadas de Jóvenes Investigadores de la Universidad de Alcalá: Ciencias, Ciencias de la Salud e Ingenierías
  1. Antonio Guerrero Ortega (ed. lit.)
  2. Germán Ros Magán (ed. lit.)
  3. Paloma Ruíz Benito (ed. lit.)
  4. Francisco Pascual Vives (ed. lit.)
  5. Cristina Tejedor Martínez (ed. lit.)
  6. Vanessa Tabernero Magro (ed. lit.)

Publisher: Editorial Universidad de Alcalá ; Universidad de Alcalá

ISBN: 978-84-18254-50-5

Year of publication: 2021

Pages: 95-102

Congress: Jornadas de Jóvenes Investigadores de la Universidad de Alcalá (8. 2021. Alcalá de Henares)

Type: Conference paper

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Abstract

Chlorpyrifos (CPF) is one of the most widely used organophosphate insecticide in agriculture. Because of the vulnerability of the developing nervous system, prenatal and early postnatal exposures to pollutants are of special concern. In this study, the human neural stem cell line hNS1 was exposed to different concentrations of the pesticide. We found that CPF induced apoptotic cell death at the highest doses tested, and promoted the generation of astroglial cells.

Data source: Dialnet