Cáncer de próstata

  1. Nalda Ariza, I. 1
  2. Peñas Pita da Veiga, M. 1
  3. Bernier García, L. 1
  4. Sánchez Cendra, C. 1
  5. Cassinello Espinosa, J. 1
  1. 1 Unidad de Oncología Médica, Hospital Universitario de Guadalajara, Guadalajara, España
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Ano de publicación: 2021

Título do exemplar: Enfermedades oncológicas (III) Tumores genitourinarios

Serie: 13

Número: 26

Páxinas: 1454-1466

Tipo: Artigo

DOI: 10.1016/J.MED.2021.02.013 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Medicine: Programa de Formación Médica Continuada Acreditado

Obxectivos de Desenvolvemento Sustentable

Resumo

Prostate cancer is the leading malignancy in men and the second most deadly. Age is the main risk factor for the development of the disease, with an average age at diagnosis of 66 years and an increase in incidence from the age of 55. The prognosis of prostate cancer depends on the stage at diagnosis, with localised disease occurring in up to 80% of cases. However, up to 20%-30% of patients will have recurrent disease. The determining factors for staging and risk stratification in prostate cancer are the extent of disease, Gleason grade and PSA levels. PSA level is also the main screening tool. Tumours confined to the prostate gland are usually treated by radical surgical and radiotherapy-based techniques, always requiring a multidisciplinary approach. Treatment in advanced stages is based in androgen deprivation therapies with androgen-receptor signalling inhibitors abiraterone and enzalutamide, as well as treatment with docetaxel, cabazitaxel and radium-223.

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Fonte de datos: Dialnet