Diseño, interacción y síntesis de compuestos biológicamente activos - Design, interaction and synthesis of bioactive compounds.
DISCOBAC


Universidad Complutense de Madrid
Madrid, EspañaPublications in collaboration with researchers from Universidad Complutense de Madrid (48)
2024
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Ni(2,2′:6′,2′′-terpyridine)2: a high-spin octahedral formal Ni(0) complex
Dalton Transactions, Vol. 53, Núm. 20, pp. 8550-8554
2023
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Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates
Journal of Organic Chemistry, Vol. 88, Núm. 11, pp. 7373-7380
2022
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Superparamagnetic Iron Oxide Nanoparticles Decorated Mesoporous Silica Nanosystem for Combined Antibiofilm Therapy
Pharmaceutics, Vol. 14, Núm. 1
2021
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Emerging Strategies in Anticancer Combination Therapy Employing Silica-Based Nanosystems
Biotechnology Journal, Vol. 16, Núm. 3
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Pd-catalyzed C(sp3)-C(sp) bond formation in iodocyclobutenes
Chemical Communications, Vol. 57, Núm. 68, pp. 8456-8459
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Recent advances toward the use of mesoporous silica nanoparticles for the treatment of bacterial infections
International Journal of Nanomedicine, Vol. 16, pp. 4409-4430
2020
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Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18
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In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases
ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801
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Mesoporous silica nanoparticles as carriers for therapeutic biomolecules
Pharmaceutics, Vol. 12, Núm. 5
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Production of MCM-41 nanoparticles with control of particle size and structural properties: Optimizing operational conditions during scale-up
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18
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Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
Scientific Reports, Vol. 10, Núm. 1
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Triflyl-assisted reductive Pd-catalyzed Tsuji-Trost type reaction
Chemical Communications, Vol. 56, Núm. 45, pp. 6070-6073
2019
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Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update
Expert Opinion on Drug Delivery, Vol. 16, Núm. 4, pp. 415-439
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Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489
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Functional mesoporous silica nanocomposites: Biomedical applications and biosafety.
International Journal of Molecular Sciences, Vol. 20, Núm. 4
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Molecular Scaffolds as Double-Targeting Agents For the Diagnosis and Treatment of Neuroblastoma
Angewandte Chemie - International Edition, Vol. 58, Núm. 10, pp. 3067-3072
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Quinoxalinetacrine QT78, a cholinesterase inhibitor as a potential ligand for Alzheimer’s disease therapy
Molecules, Vol. 24, Núm. 8
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Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones
Bioorganic Chemistry, Vol. 86, pp. 445-451
2018
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Building Block Based Construction of Membrane-Organelle Double Targeted Nanosystem for Two-Drug Delivery
Bioconjugate Chemistry, Vol. 29, Núm. 11, pp. 3677-3685
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Reversible Nanogate System for Mesoporous Silica Nanoparticles Based on Diels–Alder Adducts
Chemistry - A European Journal, Vol. 24, Núm. 27, pp. 6992-7001